Insightful AL Amyloidosis Market Report 2025 – For Product, Marketing, and Strategy Teams

 


This report is designed for companies and decision-makers seeking actionable insights on market size, growth, trends, and competitive strategies to drive expansion and success in the AL Amyloidosis industry.

#How has the al amyloidosis market size changed in recent years, and what is the outlook ahead?#
The AL amyloidosis market size has grown rapidly in recent years. It will grow from $3.11 billion in 2024 to $3.52 billion in 2025 at a compound annual growth rate (CAGR) of 13.2%.  The growth in the historic period can be attributed to growing awareness among healthcare providers about al amyloidosis, rising incidence of al amyloidosis, rising geriatric population, expansion of diagnostic centers, and improvement in cardiac imaging.

The AL amyloidosis market size is expected to see rapid growth in the next few years. It will grow to $5.74 billion in 2029 at a compound annual growth rate (CAGR) of 13.0%.  The growth in the forecast period can be attributed to rise in incidences of mutations in blood cell DNA, growing healthcare infrastructure, growing incidence of multiple myeloma, introduction of combination therapies, and increasing use of high-dose chemotherapy. Major trends in the forecast period include advancements in diagnostic techniques, technological advancements in drug delivery, advancements in blood tests, development of targeted therapies, and adoption of artificial intelligence (AI) in diagnosis.

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#What are the top economic and technological drivers pushing al amyloidosis market growth?#
The rising incidence of plasma cell disorders is expected to propel the growth of the AL amyloidosis market going forward. Plasma cell disorders are conditions where abnormal plasma cells produce excessive or abnormal antibodies, potentially causing organ damage. The rising incidence of plasma cell disorders is attributed to factors such as an aging population, increased life expectancy, and advancements in diagnostic technologies. AL amyloidosis is a condition that arises from plasma cell disorders, specifically the overproduction of abnormal light chain proteins, which can lead to the accumulation of amyloid deposits in organs and tissues, further exacerbating the effects of plasma cell dyscrasias. For instance, in August 2024, according to the reports published by The American Cancer Society (ACS), a US-based nonprofit organization, in 2024, about 35,780 new cases of multiple myeloma are expected to be diagnosed (19,520 in men and 16,260 in women), and around 12,540 deaths are projected, with 7,020 in men and 5,520 in women. Therefore, the rising incidence of plasma cell disorders is driving the growth of the AL amyloidosis market.

#How is the al amyloidosis market segmented by product, application, and end-user?#
The AL amyloidosis market covered in this report is segmented –

1) By Treatment: Chemotherapy, Supportive Care, Surgery, Stem Cell Transplant, Targeted Therapy
2) By Drugs: Transthyretin Transport Inhibitor, Immunomodulatory Drugs, Monoclonal Antibodies, Proteasome Inhibitors, Other Drugs
3) By Route Of Administration: Intravenous, Oral
4) By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies

Subsegments:
1) By Chemotherapy: Conventional Chemotherapy Agents, High-Dose Chemotherapy
2) By Supportive Care: Pain Management, Organ-specific Supportive Care (Cardiac, Renal)
3) By Surgery: Organ Transplantation, Debulking Surgery
4) By Stem Cell Transplant: Autologous Stem Cell Transplant, Allogeneic Stem Cell Transplant
5) By Targeted Therapy: Monoclonal Antibodies, Proteasome Inhibitors, Kinase Inhibitors

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#What evolving trends are creating new opportunities in the al amyloidosis market?#
Major companies operating in the AL amyloidosis market are focusing on developing innovative therapies such as next-generation B-cell maturation antigen (BCMA)-directed CAR T-cell therapy to improve treatment efficacy and patient outcomes. Next-generation BCMA-directed CAR T-cell therapy refers to an advanced form of immunotherapy that involves engineering a patient's T cells to target and attack BCMA on the surface of cancer cells, specifically in multiple myeloma. For instance, in September 2023, Immix Biopharma Inc., a US-based biopharmaceutical company, received approval from the U.S. Food and Drug Administration (FDA) for NXC-201 for the treatment of a life-threatening blood disorder, Amyloid Light Chain (AL) Amyloidosis. NXC-201 is a next-generation CAR-T cell therapy being tested in clinical trials for the treatment of amyloid light chain (AL) amyloidosis, showing promising results with a 100% hematologic response rate and organ improvements in patients who had failed previous treatments.

#Which leading companies are dominating the al amyloidosis market landscape?#
Major companies operating in the AL amyloidosis market are  Johnson & Johnson, AbbVie Inc., Sanofi S.A., Bristol-Myers Squibb Company, AstraZeneca PLC, Takeda Pharmaceutical Company Limited, Boehringer Ingelheim International GmbH, Astellas Pharma Inc., Genmab A/S, Alexion Pharmaceuticals Inc., Alnylam Pharmaceuticals Inc., Prothena Corporation plc, BridgeBio Pharma Inc., Sorrento Therapeutics Inc., Ionis Pharmaceuticals Inc., Ultromics Ltd, Neurimmune AG, Immix Biopharma Inc., Oncopeptides AB, Attralus Inc.

#Which geographic areas are expected to offer the highest growth opportunities in theal amyloidosis market?#
North America was the largest region in the AL amyloidosis market in 2024. The regions covered in the AL amyloidosis market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

#How Can Companies Use The AL Amyloidosis Market Report to Drive Business Results?#
This report provides actionable insights tailored for business use—not academic analysis. Companies can leverage the data to:
• Time market entry or expansion using growth forecasts and CAGR trends.
• Develop competitive products by tracking key technology shifts and user preferences.
• Tailor regional strategies with in-depth geographic data and local market dynamics.
• Benchmark and plan partnerships using competitive landscape insights.

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For companies needing more tailored intelligence, The Business Research Company offers customized consulting and data services. Whether you're entering new regions, launching innovative products, or assessing M&A opportunities, our experts can develop actionable insights specific to your business objectives.

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