Locally Advanced Pancreatic Cancer Market Report 2025 – Strategic Insights for Companies Seeking Expansion, Growth & Competitive Advantage

  Locally Advanced Pancreatic Cancer Market Size and growth rate 2025 to 2029: Graph

 


For business leaders, corporate strategists, and growth-focused teams — this report delivers deep market intelligence, forecasts, segmentation, and competitor insights to guide your decisions through 2034.
 
 #What are the growth projections for the locally advanced pancreatic cancer market from 2024 to 2029?#
 The locally advanced pancreatic cancer market size has grown rapidly in recent years. It will grow from $0.95 billion in 2024 to $1.05 billion in 2025 at a compound annual growth rate (CAGR) of 10.9%. The growth in the historic period can be attributed to increase in awareness of pancreatic cancer, improved chemotherapy regimens, growth in use of targeted therapies, rise in incidence of pancreatic cancer, development of combination treatment protocols, and enhanced supportive care options.
 
 The locally advanced pancreatic cancer market size is expected to see rapid growth in the next few years. It will grow to $1.57 billion in 2029 at a compound annual growth rate (CAGR) of 10.5%. The growth in the forecast period can be attributed to increase in awareness of pancreatic cancer, improved chemotherapy regimens, growth in use of targeted therapies, rise in incidence of pancreatic cancer, development of combination treatment protocols, and enhanced supportive care options. Major trends in the forecast period include advancements in immunotherapy, development of targeted therapies, enhanced precision radiation techniques, improved diagnostic imaging, adoption of minimally invasive surgical approaches, integration of artificial intelligence in treatment planning, and advancements in combination therapy.
 
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 #What strategic initiatives by market players are driving locally advanced pancreatic cancer industry growth?#
 The increase in tobacco consumption is expected to drive the growth of the locally advanced pancreatic cancer markets going forward. Tobacco is a plant whose leaves are used in products such as cigarettes and cigars. It contains nicotine, which is addictive and is linked to serious health issues such as cancer and heart disease. The rising tobacco consumption is driven by factors such as easy access, affordability, tobacco marketing, social acceptance in some areas, and stress-related smoking. Tobacco consumption is a significant risk factor for the development of locally advanced pancreatic cancer, as it contributes to the increased incidence of pancreatic malignancies. For instance, in January 2024, according to the Global Action to End Smoking, a US-based non-profit organization for research related to end the smoking epidemic, in 2022, around 62.9 million adults in the U.S. used tobacco, ranking it 4th globally and 1st in the Americas. Further, around 11.5% of U.S. adults (28.3 million) smoked cigarettes, with higher rates among males (13.1%) than females (10.1%). Therefore, the increase in tobacco consumption is driving the growth of the locally advanced pancreatic cancer market.
 
 #What emerging segments are shaping the future landscape of the locally advanced pancreatic cancer industry?#
 The locally advanced pancreatic cancer market covered in this report is segmented –
 
 1) By Therapy: Chemotherapy, Immunotherapy, Radiation Therapy, Surgery
 2) By Route Of Administration: Oral, Injectables, Other Route Of Administrations
 3) By End-User: Hospital, Specialty Clinics, Research Institutions, Other End-Users
 
 Subsegments:
 1) By Chemotherapy: Gemcitabine-based Chemotherapy, FOLFIRINOX Chemotherapy
 2) By Immunotherapy: Immune Checkpoint Inhibitors, Cancer Vaccines
 3) By Radiation Therapy: External Beam Radiation Therapy, Stereotactic Body Radiation Therapy (SBRT)
 4) By Surgery: Pancreaticoduodenectomy (Whipple Procedure), Distal Pancreatectomy, Total Pancreatectomy
 
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 #How are emerging trends transforming the locally advanced pancreatic cancer market dynamics?#
 Major companies operating in the locally advanced pancreatic cancer market are focusing on developing innovative products, such as orphan drugs, to enhance treatment options, improve patient outcomes, and address the unmet medical needs associated with this aggressive disease. Orphan drugs are designed to treat rare diseases affecting a small group of people and are incentivized by authorities with benefits such as tax reductions and market exclusivity to promote their development. For instance, in January 2025, Actuate Therapeutics Inc., a US-based biopharmaceutical company, announced that its Elraglusib, a new GSK-3β inhibitor, has received Orphan Drug Designation from both the European Medicines Agency (EMA) and US Food and Drug Administration (FDA) for treating pancreatic ductal adenocarcinoma (PDAC) (a potential types of locally advanced pancreatic cancer). This recognition highlights its potential to fill a critical gap in treating this severe cancer, especially after promising Phase 2 trial results showing significant clinical improvements and anti-tumor effects in metastatic PDAC patients.
 
 #How are key players in the locally advanced pancreatic cancer market strengthening their market position?#
 Major companies operating in the locally advanced pancreatic cancer market are Pfizer Inc., F. Hoffmann-La Roche Ltd., Merck KGaA, AbbVie Inc., Bayer Inc., Bristol-Myers Squibb Company, AstraZeneca plc, Abbott Laboratories, Novartis AG, GSK plc, Ipsen Biopharmaceuticals Inc., Lupin Limited, NovoCure Limited, Theratechnologies Inc., XBiotech, Prestige Biopharma, OSE Immunotherapeutics, Helix Biopharma Corporation, Fawn Incorporation, Eli Lilly and Co
 
 #Which geographic areas are contributing significantly to the growth of the locally advanced pancreatic cancer sector?#
 North America was the largest region in the locally advanced pancreatic cancer market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the locally advanced pancreatic cancer market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
 
 #How Can Companies Use The Locally Advanced Pancreatic Cancer Market Report to Drive Business Results?#
 This report provides actionable insights tailored for business use — not academic analysis. Companies can leverage the data to:
 • Time market entry or expansion using growth forecasts and CAGR trends.
 • Develop competitive products by tracking key technology shifts and user preferences.
 • Tailor regional strategies with in-depth geographic data and local market dynamics.
 • Benchmark and plan partnerships using competitive landscape insights.
 
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