Paraganglioma Forecast Report 2025 – Designed for Product & Growth Teams
This report is designed for companies and decision-makers seeking actionable insights on market size, growth, trends, and competitive strategies to drive expansion and success in the Paraganglioma industry.
#What is the current market size of the paraganglioma industry, and what growth rate is it expected to achieve?#
The paraganglioma market size has grown strongly in recent years. It will grow from $2.89 billion in 2024 to $3.03 billion in 2025 at a compound annual growth rate (CAGR) of 5.0%. The growth in the historic period can be attributed to advancements in diagnostic imaging, increasing awareness & screening programs, regulatory approvals for targeted therapies, growth in specialized treatment centers, and advancements in genetic testing.
The paraganglioma market size is expected to see strong growth in the next few years. It will grow to $3.64 billion in 2029 at a compound annual growth rate (CAGR) of 4.7%. The growth in the forecast period can be attributed to emerging targeted therapies & immunotherapies, expansion of radiopharmaceuticals, rising prevalence of genetic disease, growing investments in rare disease research, and improved healthcare access in emerging markets. Major trends in the forecast period include advancements in targeted therapies, expansion of radiopharmaceuticals, the rise of immunotherapy approaches, improved artificial intelligence (AI) in diagnostics, and the development of minimally invasive surgical techniques.
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#What are the major drivers contributing to the growth of the paraganglioma market?#
The increasing investments on oncology research and medicine is expected to propel the growth of the paraganglioma market going forward. Investments in oncology research and medicine refer to financial allocations made by governments, pharmaceutical companies, research institutions, and private investors to advance the understanding, prevention, diagnosis, and treatment of cancer. The increasing investments in oncology research and medicine are due to the rising global cancer burden, advancements in precision medicine, growing demand for innovative therapies, expanding clinical trials, government and private funding initiatives, and the development of targeted and immunotherapy treatments. Investments in oncology research and medicine support paraganglioma by driving advancements in early diagnosis, enhancing treatment options such as targeted therapies and immunotherapy, funding clinical trials for more effective drugs, improving pediatric cancer care infrastructure, and fostering innovative research to better understand the disease’s biology and progression. For instance, in May 2024, according to the IQVIA, an India-based information technology company providing advanced analytics, global spending on cancer medicine rose to $223 billion in 2023, marking a $25 billion increase from 2022, and is expected to reach $409 billion by 2028. Therefore, the increasing investments on oncology research and medicine drives the paraganglioma market.
#What are the major market segments driving the growth of the paraganglioma industry?#
The paraganglioma market covered in this report is segmented –
1) By Type: Sympathetic Paragangliomas, Parasympathetic Paragangliomas, Caroid Paragangliomas, Cervical Paragangliomas, Jugular Paragangliomas, Secretory Paragangliomas, Temporal Paragangliomas
2) By Origin: Head And Neck, Abdomen, Pelvis, Other Origins
3) By Treatment Type: Peptide Receptor Radionuclide Therapy, Surgery, Chemotherapy, Radiation Therapy, Other Treatment Types
4) By Distribution Channel: Hospital Pharmacies, Drug Stores And Retail Pharmacies, Online Pharmacies
5) By End-User: Hospitals, Specialty Clinics, Cancer Research Institutes, Other End-Users
Subsegments:
1) By Sympathetic Paragangliomas: Adrenal Sympathetic Paragangliomas, Extra-Adrenal Sympathetic Paragangliomas
2) By Parasympathetic Paragangliomas: Head And Neck Parasympathetic Paragangliomas, Thoracic Parasympathetic Paragangliomas
3) By Carotid Paragangliomas: Unilateral Carotid Paragangliomas, Bilateral Carotid Paragangliomas
4) By Cervical Paragangliomas: Vagal Paragangliomas, Hypoglossal Paragangliomas
5) By Jugular Paragangliomas: Type A, Type B, Type C, Type D
6) By Secretory Paragangliomas: Catecholamine-Secreting Paragangliomas, Non-Catecholamine-Secreting Paragangliomas
7) By Temporal Paragangliomas: Tympanic Paragangliomas, Mastoid Paragangliomas
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#What are the most notable trends influencing investment in the paraganglioma sector?#
Major companies operating in the paraganglioma market are focusing on developing advanced therapies such as oral hypoxia-inducible factor-2 alpha (HIF-2α) inhibitors to offer targeted therapy options for patients with paraganglioma. An oral HIF-2α inhibitor is a targeted therapy that suppresses HIF-2α activity, a key factor in tumor growth under low-oxygen conditions, helping to slow the progression of cancers like paraganglioma. For instance, in January 2025, Merck, a US-based biopharmaceutical company, announced a priority review for its supplemental new drug application for Welireg (belzutifan), which is granted by the U.S. Food and Drug Administration (FDA), a US-based government agency. It is designed for adult and pediatric patients (12 years and older) with advanced, unresectable, or metastatic pheochromocytoma and paraganglioma (PPGL). The sNDA is based on objective response rate (ORR) and duration of response (DOR) data from the Phase 2 LITESPARK-015 trial.
#Who are the key market players contributing to the growth of the paraganglioma industry?#
Major companies operating in the paraganglioma market are F. Hoffmann-La Roche Ltd., Merck & Co. Inc. , Mount Sinai, Penn Medicine, Stanford Health Care, St. Jude Children’s Research Hospital, UT Health San Antonio, The University of Chicago Medical Center, Fred Hutchinson Cancer Center, Florida Cancer Specialists & Research Institute, Invitae Corp., Clinigen Group plc, Fulgent Genetics, Dana-Farber Cancer Institute Inc., Oncology Hematology Care Inc., Enterome , National Institutes of Health Clinical Center, Progenics Pharmaceuticals Inc., Pheo Para Alliance, Saint John’s Cancer Institute
#Which regions are leading the growth of the paraganglioma market globally?#
North America was the largest region in the paraganglioma market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the paraganglioma market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
#How Can Companies Use The Paraganglioma Market Report to Drive Business Results?#
This report provides actionable insights tailored for business use — not academic analysis. Companies can leverage the data to:
• Time market entry or expansion using growth forecasts and CAGR trends.
• Develop competitive products by tracking key technology shifts and user preferences.
• Tailor regional strategies with in-depth geographic data and local market dynamics.
• Benchmark and plan partnerships using competitive landscape insights.
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