Restless Leg Syndrome Market Report 2025 – Strategic Insights for Companies Seeking Expansion, Growth & Competitive Advantage

 

  Restless Leg Syndrome Market Size and growth rate 2025 to 2029: Graph


For business leaders, corporate strategists, and growth-focused teams — this report delivers deep market intelligence, forecasts, segmentation, and competitor insights to guide your decisions through 2034.
 
 #What are the growth projections for the restless leg syndrome market from 2024 to 2029?#
 The restless leg syndrome market size has grown rapidly in recent years. It will grow from $1.91 billion in 2024 to $2.17 billion in 2025 at a compound annual growth rate (CAGR) of 13.8%. The growth in the historic period can be attributed to increasing rates of alcohol, increase in health insurance coverage, availability of over-the-counter medications, increasing public health initiatives and surge in mental health issues.
 
 The restless leg syndrome market size is expected to see rapid growth in the next few years. It will grow to $3.59 billion in 2029 at a compound annual growth rate (CAGR) of 13.4%. The growth in the forecast period can be attributed to increase in healthcare investment, awareness and education campaigns, increase in early diagnosis, increase in government funding, and enhanced clinical trial participation. Major trends in the forecast period include ai-powered personalized treatment plans, next-generation neurostimulation devices, deep learning algorithms for diagnosis, brainwave modulation technology, and wearable exoskeletons for leg movements.
 
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 #What strategic initiatives by market players are driving restless leg syndrome industry growth?#
 The increasing prevalence of iron deficiency is expected to propel the growth of the restless leg syndrome market going forward. Iron deficiency refers to a condition in which the body lacks enough iron to produce sufficient healthy red blood cells, leading to symptoms such as fatigue, weakness, and pale skin. The increasing prevalence of iron deficiency is due to factors such as poor dietary intake, blood loss, malabsorption disorders, and increased iron requirements during pregnancy or growth. Restless leg syndrome treatment often involves iron supplementation or dietary adjustments, which not only help alleviate the uncomfortable urges and sensations but also work to correct underlying iron deficiency by replenishing iron stores in the body, improving red blood cell production, and restoring proper neurological function. For instance, in January 2025, according to the Nation Health Service England, an England-based government agency, in the 2023–24 period, there were 191,927 admissions due to iron deficiency, reflecting an 11% increase compared to 2022–23. Therefore, the increasing prevalence of iron deficiency drives the growth of the restless leg syndrome market.
 
 #What emerging segments are shaping the future landscape of the restless leg syndrome industry?#
 The restless leg syndrome market covered in this report is segmented –
 
 1) By Type: Primary Restless Legs Syndrome, Secondary Restless Legs Syndrome
 2) By Treatment Type: Medicine And Devices, Surgery
 3) By Route Of Administration: Oral, Injectable
 4) By Distribution Channel: Hospital Pharmacy, Retail Pharmacy, Online Pharmacy
 5) By Application: Neurological Treatment, Sleep Disorders, Movement Disorders, Symptom Management
 
 Subsegments:
 1) By Primary Restless Legs Syndrome: Idiopathic Restless Legs Syndrome, Hereditary Restless Legs Syndrome
 2) By Secondary Restless Legs Syndrome: Iron Deficiency-related Restless Legs Syndrome, Chronic Kidney Disease-related Restless Legs Syndrome, Pregnancy-related Restless Legs Syndrome, Medication-induced Restless Legs Syndrome
 
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 #What technological trends are expected to redefine the restless leg syndrome market?#
 Major companies operating in the restless leg syndrome (RLS) market are focused on developing innovative solutions, such as novel non-invasive therapies, to improve symptom management and enhance patient outcomes. Novel non-invasive therapies refer to innovative medical treatments that do not require surgery or penetration of the skin, aiming to provide relief from various conditions through advanced techniques such as electrical stimulation, light therapy, or external devices. For instance, in April 2023, Varco Leg Care, an India-based consumer health-technology company, received FDA De Novo approval for its NTX100 Tonic Motor Activation (TOMAC) System. The NTX100 Tonic Motor Activation (TOMAC) System is designed to treat moderate to severe symptoms of restless legs syndrome (RLS) and improve sleep quality in patients who do not respond to medications. The device works by electrically activating the peroneal nerves on both sides of the body to produce tonic, sustained muscle activation, which is compatible with sleep. This activation helps suppress the symptoms of restless leg syndrome (RLS).
 
 #How are key players in the restless leg syndrome market strengthening their market position?#
 Major companies operating in the restless leg syndrome market are Pfizer Inc., Roche Holding AG, Merck & Co Inc., Novartis International AG, GlaxoSmithKline plc, Teva Pharmaceutical Industries Ltd., Boehringer Ingelheim International GmbH, Baxter International Inc., Astellas Pharma Inc., UCB S.A., Kyowa Kirin Co Ltd., Amneal Pharmaceuticals Inc., Lupin Pharmaceuticals Inc., Alembic Pharmaceuticals Limited, Mundipharma International Limited, Azurity Pharmaceuticals LLC, Otsuka Pharmaceutical Co Ltd., Horizon Therapeutics plc, Mylan N.V., Apollo Pharmacy Limited
 
 #Which geographic areas are contributing significantly to the growth of the restless leg syndrome sector?#
 Europe was the largest region in the restless leg syndrome market in 2024. North-America is expected to be the fastest-growing region in the forecast period. The regions covered in the restless leg syndrome market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
 
 #How Can Companies Use The Restless Leg Syndrome Market Report to Drive Business Results?#
 This report provides actionable insights tailored for business use — not academic analysis. Companies can leverage the data to:
 • Time market entry or expansion using growth forecasts and CAGR trends.
 • Develop competitive products by tracking key technology shifts and user preferences.
 • Tailor regional strategies with in-depth geographic data and local market dynamics.
 • Benchmark and plan partnerships using competitive landscape insights.
 
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 #Need Customized Data On Restless Leg Syndrome Market?#
 For companies needing more tailored intelligence, The Business Research Company offers customized consulting and data services. Whether you’re entering new regions, launching innovative products, or assessing M&A opportunities, our experts can develop actionable insights specific to your business objectives.
 
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